Project Review

Review Observed Facts And Committee Assumptions

Which project mix best advances LifeArc's MND validation and early-detection goals in the current round? Select a row and inspect the three-layer split: observed facts, committee assumptions, and calculated outputs.

How To Use This Page

Use the project drawer on the right as the canonical interpretation layer.

1. Start With Facts

Treat public stage, public funding facts, evidence summary, and source references as the observed layer.

2. Then Review Assumptions

Requested budgets, screening passes, rubric scores, and milestone costs are committee modelling inputs used to run the simulator consistently.

3. Read Outputs Last

Quality, milestone, cost-effectiveness, need, frontier, and scenario allocations are calculated outputs derived from the formula layer.

Observed facts should never be confused with round-sized budget assumptions.
All real rows remain explicitly marked as public-fact-backed cases.
Synthetic rows exist only to make the committee simulator more stress-testable.
Hybrid allocation on this page uses the DEAP 40/35/25 weight formula plus optimal-budget caps.

Portfolio Review Grid

Select a project row to inspect observed facts, committee assumptions, and calculated outputs.

ProjectHubTypePublic StageRequestedMin ViableOptimalQualityHybrid Allocation

MND STaR target validation programme

RL1

LifeArcRealearly-stage preclinical validation£90,000£55,000£85,0007.05£52,828

Primer Fund blood test for early MND detection

RL2

LifeArcRealvalidation / biomarker development£65,000£35,000£60,0006.75£36,550

AgriTwin

P2

LifeArcSyntheticmvp£60,000£40,000£55,0006.85£41,999

GridPatch

P5

LifeArcSyntheticmvp / early pilots£100,000£60,000£90,0006.95£48,623

MND STaR target validation programme

RL1 · LifeArc

Observed Facts

Public stage

early-stage preclinical validation

Evidence summary

LifeArc states that MND STaR is a two-year collaboration with King's College London, includes up to GBP 1.5 million funding, and aims to deliver eight target-validation data packages.

Public funding fact

£1,500,000

Source references

  • LifeArc programme overview: MND STaR

Committee Assumptions

Budget assumptions

Requested £90,000

Min viable £55,000

Optimal £85,000

Screening checks

Mandate Pass

Team Pass

Complete Pass

Budget Pass

Milestone Pass

Compliance Pass

Criterion scores

Strategic fit 9/10

Team 8/10

Feasibility 7/10

Market 6/10

Evidence 7/10

Milestone readiness 7/10

Capital efficiency 7/10

Frontier potential 8/10

Risk penalty 5/10

Milestone assumptions

Deliver validated MND target package

Cost £55,000 · Importance 9/10

Readiness 7/10 · Confidence 7/10 · Unlock value 9/10

Calculated Outputs

Quality score

7.05

Milestone score

8.10

Cost-effectiveness

0.147

Need score

24,255

Frontier score

7.90

Hybrid allocation

£52,828

Weight 29.3%